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Article

SpeedSeq: ultra-fast personal genome analysis and interpretation.

Nature methods - 1 Oct 2015

Chiang Colby, Layer Ryan M, Faust Gregory G, Lindberg Michael R, Rose David B, Garrison Erik P, Marth Gabor T, Quinlan Aaron R, Hall Ira M

Abstract excerpt

SpeedSeq is an open-source genome analysis platform that accomplishes alignment, variant detection and functional annotation of a 50× human genome in 13 h on a low-cost server and alleviates a bioinformatics bottleneck that typically demands weeks of computation with extensive hands-on expert inv...

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PMID: 26258291
DOI: 10.1038/nmeth.3505
PMCID: PMC4589466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26258291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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