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Article

Determinants in HIV-2 Env and tetherin required for functional interaction.

Retrovirology - 7 Aug 2015

Exline Colin M, Yang Su Jung, Haworth Kevin G, Rengarajan Srinivas, Lopez Lisa A, Droniou Magali E, Seclen Eduardo, Cannon Paula M

Abstract excerpt

BACKGROUND: The interferon-inducible factor BST-2/tetherin blocks the release of nascent virions from the surface of infected cells for certain enveloped virus families. The primate lentiviruses have evolved several counteracting mechanisms which, in the case of HIV-2, is a function of its Env protein. We sought to further understand the features of the Env protein and tetherin that are important for this...

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Identifiers

PMID: 26248668
DOI: 10.1186/s12977-015-0194-0
PMCID: PMC4528709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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