Article
Weak Interactions between Salmonella enterica FlhB and Other Flagellar Export Apparatus Proteins Govern Type III Secretion Dynamics.
PloS one - 1 Jan 2015
McMurry Jonathan L, Minamino Tohru, Furukawa Yukio, Francis Joshua W, Hill Stephanie A, Helms Katy A, Namba Keiichi
Abstract excerpt
The bacterial flagellum contains its own type III secretion apparatus that coordinates protein export with assembly at the distal end. While many interactions among export apparatus proteins have been reported, few have been examined with respect to the differential affinities and dynamic relationships that must govern the mechanism of export. FlhB, an integral membrane protein, plays critical roles in both...
Topics
- Adenosine Triphosphate
- Algorithms
- Bacterial Proteins
- Computer Simulation
- Flagella
- Immunoblotting
- Kinetics
- Membrane Proteins
- Mutation
- Protein Binding
- Protein Multimerization