The FliI ATPase couples ATP hydrolysis to substrate switching in bacterial flagellar type-III secretion.

Abstract excerpt

Bacterial flagella are assembled by a specialized type-III secretion system that exports structural subunits in a defined order. While the ATPase FliI is known to couple ATP hydrolysis to substrate translocation, its role in the transition between early and late secretion stages has remained unclear. Here, we systematically analyzed Salmonella enterica strains with mutations in the catalytic domain of FliI and...

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