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Article

Functional and Structural Impact of ATP-Binding Cassette Transporter A1 R219K and I883M Gene Polymorphisms in Obese Children and Adolescents.

Molecular diagnosis & therapy - 1 Aug 2015

Fawzy Manal S, Alhadramy Osama, Hussein Mohammad H, Ismail Hussein M, Ismail Nesreen M, Biomy Nouran M, Toraih Eman A

Abstract excerpt

INTRODUCTION: Obesity is a serious medical condition that affects children and adolescents. ATP-binding cassette transporter A1 (ABCA1) protein is known to mediate the transport of intracellular cholesterol and phospholipids across the cell membranes. Thus, we aimed to investigate the association between ABCA1 gene polymorphisms and overweight/obesity risk, and to evaluate their relation to the lipid profile....

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Source

Identifiers

PMID: 26243156
DOI: 10.1007/s40291-015-0150-7

Genes

ABCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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