Article
R219K polymorphism of ATP binding cassette transporter A1 related with low HDL in overweight/obese Thai males.
Archives of medical research - 1 Nov 2007
Kitjaroentham Anong, Hananantachai Hathairad, Tungtrongchitr Anchalee, Pooudong Somchai, Tungtrongchitr Rungsunn
Abstract excerpt
BACKGROUND: ATP binding cassette transporter A1 (ABCA1) plays a role in the initial stage of removing cholesterol from the body via cholesterol efflux. Mutations of this gene cause wide-ranging HDL deficiency, as evident in Tangier disease and familial hypoalphalipoproteinemia. The aim of this study was to elucidate whether the presence of ABCA1 gene polymorphism could be a risk factor for overweight/obesity....
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