Article
Characterization of acinar airspace involvement in asthmatic patients by using inert gas washout and hyperpolarized (3)helium magnetic resonance.
The Journal of allergy and clinical immunology - 1 Feb 2016
Gonem Sherif, Hardy Steven, Buhl Niels, Hartley Ruth, Soares Marcia, Kay Richard, Costanza Rino, Gustafsson Per, Brightling Christopher E, Owers-Bradley John, Siddiqui Salman
Abstract excerpt
BACKGROUND: The multiple-breath inert gas washout parameter acinar ventilation heterogeneity (Sacin) is thought to be a marker of acinar airway involvement but has not been validated by using quantitative imaging techniques in asthmatic patients. OBJECTIVE: We aimed to use hyperpolarized (3)He diffusion magnetic resonance at multiple diffusion timescales and quantitative computed tomographic (CT) densitometry to...
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