Article
Phenotyping asthma and/or chronic obstructive pulmonary disease using 129Xe MRI and comprehensive physiologic testing.
American journal of respiratory and critical care medicine - 1 Jan 2026
Marshall Helen, Smith Laurie J, Biancardi Alberto M, Collier Guilhem J, Chan Ho-Fung, Hughes Paul J C, Brook Martin L, Astley Joshua R, Munro Ryan, Rajaram Smitha, Swift Andrew J, Capener David, Bray Jody, Ball James E, Rodgers Oliver, Jakymelen Demi-Jade, Tahir Bilal A, Rao Madhwesha, Norquay Graham, Weatherley Nicholas D, Armstrong Leanne, Hardaker Latife, Papi Alberto, Reddel Helen K, Müllerová Hana, Hughes Rod, Wild Jim M
Abstract excerpt
RATIONALE: Asthma and chronic obstructive pulmonary disease (COPD) significantly overlap by conventional diagnostic criteria, yet important treatment differences remain, and people with both asthma and COPD (asthma + COPD) have worse clinical outcomes than people with a single diagnosis. Hyperpolarized xenon-129 magnetic resonance imaging (129Xe MRI) and pulmonary function tests (PFTs) are sensitive to lung...
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