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Article

Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo.

Molecular medicine reports - 1 Oct 2015

Zhang Jian-Feng, Qu Li-Shuai, Qian Xue-Fen, Xia Bei-Lei, Mao Zhen-Biao, Chen Wei-Chang

Abstract excerpt

The epithelial‑to‑mesenchymal transition (EMT) has been noted as a critical event in the early step of cancer metastasis. Recent studies showed that nuclear transcription factor caudal type homeobox transcription factor 2 (CDX2) is a prognostic factor, which acts as a marker of good outcome in gastric cancer (GC) patients. However, the association between CDX2 expression and EMT has remained to be fully...

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Source

Identifiers

PMID: 26238762
DOI: 10.3892/mmr.2015.4114

Genes

CDX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo.PMID 26238762Read ↗

New insights into the functions and localization of the homeotic gene CDX2 in gastric cancer.Semantic proximity Read ↗

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CDX2 is involved in microRNA‑associated inflammatory carcinogenesis in gastric cancerSemantic proximity Read ↗

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