Article
A novel 3D method of locomotor analysis in adult zebrafish: Implications for automated detection of CNS drug-evoked phenotypes.
Journal of neuroscience methods - 30 Nov 2015
Stewart Adam Michael, Grieco Fabrizio, Tegelenbosch Ruud A J, Kyzar Evan J, Nguyen Michael, Kaluyeva Aleksandra, Song Cai, Noldus Lucas P J J, Kalueff Allan V
Abstract excerpt
BACKGROUND: Expanding the spectrum of organisms to model human brain phenotypes is critical for our improved understanding of the pathobiology of neuropsychiatric disorders. Given the clear limitations of existing mammalian models, there is an urgent need for low-cost, high-throughput in-vivo technologies for drug and gene discovery. NEW METHOD: Here, we introduce a new automated method for generating 3D (X,Y,Z)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.