Diverse Defence Systems and Prophages in Human-Associated Bifidobacterium Species Reveal "Arms Race" Dynamics

Abstract excerpt

Bacteria of the genus Bifidobacterium are pivotal for human health, especially in early life, where they dominate the gut microbiome in healthy infants. Bacteriophages, viruses of bacteria, are drivers of gut bacterial composition in the human gut and could affect bifidobacterial abundance. Here, we use a bioinformatics approach to explore the direct interactions occurring between human-associated Bifidobacterium...

Topics

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• Bifidobacterium
• Chromosomes, Bacterial
• Clustered Regularly Interspaced Short Palindromic Repeats
• CRISPR-Cas Systems
• DNA
• Evolution, Molecular
• Genome, Bacterial
• Prophages

Identifiers and source

Literature Corpus work

746d6f83-08f6-5d6a-897d-d85524949096

DOI

10.1101/2025.01.20.633837