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Article

Microbial Population Differentials between Mucosal and Submucosal Intestinal Tissues in Advanced Crohn's Disease of the Ileum

29 Jul 2015

Abstract excerpt

Since Crohn's disease is a transmural disease, we hypothesized that examination of deep submucosal tissues directly involved in the inflammatory disease process may provide unique insights into bacterial populations transgressing intestinal barriers and bacterial populations more representative of the causes and agents of the disease. We performed deep 16s microbiota sequencing on isolated ilea mucosal and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26222621
DOI: 10.1371/journal.pone.0134382

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