Article
Crohn's Disease Differentially Affects Region-Specific Composition and Aerotolerance Profiles of Mucosally Adherent Bacteria.
Inflammatory bowel diseases - 19 Nov 2020
Shahir Nur M, Wang Jeremy R, Wolber E Ashley, Schaner Matthew S, Frank Daniel N, Ir Diana, Robertson Charles E, Chaumont Nicole, Sadiq Timothy S, Koruda Mark J, Rahbar Reza, Nix B Darren, Newberry Rodney D, Sartor R Balfour, Sheikh Shehzad Z, Furey Terrence S
Abstract excerpt
BACKGROUND: The intestinal microbiota play a key role in the onset, progression, and recurrence of Crohn disease (CD). Most microbiome studies assay fecal material, which does not provide region-specific information on mucosally adherent bacteria that directly interact with host systems. Changes in luminal oxygen have been proposed as a contributor to CD dybiosis. METHODS: The authors generated 16S rRNA data...
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