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Article

Circulating microRNAs in obese and lean heart failure patients: A case–control study with computational target prediction analysis

26 Jul 2015

Abstract excerpt

AIMS: MicroRNAs (miRs) regulate processes involved in both cardiac remodeling and obesity. We investigated if the expression of selected miRs in patients with heart failure (HF) is influenced by the presence of obesity. METHODS: In this case-control study, we compared plasma levels of miR-21, -130b, -221, -423-5p, and the -221/-130b ratio in 57 age- and gender-matched subjects: 40 HF patients (20 obese HF and 20...

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PMID: 26211628
DOI: 10.1016/j.gene.2015.07.068

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