Characteristics and Outcomes of Patients with Lung Cancer Harboring Multiple Molecular Alterations: Results from the IFCT Study Biomarkers France.

doi:10.1016/j.jtho.2017.02.001

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Article

Characteristics and Outcomes of Patients with Lung Cancer Harboring Multiple Molecular Alterations: Results from the IFCT Study Biomarkers France.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2017

Guibert Nicolas, Barlesi Fabrice, Descourt Renaud, Léna Hervé, Besse Benjamin, Beau-Faller Michèle, Mosser Jean, Pichon Eric, Merlio Jean-Philippe, Ouafik L'Houcine, Guichard François, Mastroianni Bénédicte, Moreau Lionel, Wdowik Annie, Sabourin Jean-Christophe, Lemoine Antoinette, Missy Pascale, Langlais Alexandra, Moro-Sibilot Denis, Mazières Julien

Abstract excerpt

INTRODUCTION: Little is known about the prevalence, prognosis, and response to treatment of advanced NSCLC harboring multiple genomic alterations. METHODS: The French Biomarkers France database, which includes 17,664 patients, was used. The prevalence of multiple alterations, their associations, their impact on prognosis (overall survival [OS]), and their response to targeted or conventional treatments...

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PMID: 28189832
DOI: 10.1016/j.jtho.2017.02.001

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