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Article

Cell Receptors for Influenza a Viruses and the Innate Immune Response

1 Jan 2012

Abstract excerpt

The interaction of the hemagglutinin (HA) of the influenza A viruses (IAV) with the cell surface is a key factor for entry of the virus and productive infection of the cell. This glycoprotein has affinity for sialic acids (SA), and different strains present specificity for SA bound through α2,3 or α2,6 linkages to the underlying sugar chain, which is usually related with host and cell tropism. Nucleic acid...

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PMID: 22536196
DOI: 10.3389/fmicb.2012.00117

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