Article
Carriage of Mutant Dihydrofolate Reductase and Dihydropteroate Synthase Genes among Plasmodium falciparum Isolates Recovered from Pregnant Women with Asymptomatic Infection in Lagos, Nigeria.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2015
Iwalokun Bamidele Abiodun, Iwalokun Senapon O, Adebodun Victor, Balogun Modinat
Abstract excerpt
OBJECTIVE: To assess N51I, C59R and S108N polymorphisms of dihydrofolate reductase (dhfr) and A437G and K540E of dihydropteroate synthase (dhps) genes of P. falciparum isolates recovered from pregnant women with asymptomatic malaria in a coastal setting in Nigeria. SUBJECTS AND METHODS: A total of 107 consenting and consecutively enrolled pregnant women (mean age ± standard deviation, 26.6 ± 4.5 years) attending...
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