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Article

Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus.

Scientific reports - 23 Jul 2015

Lu Hsiao-Ling, Wang Jonathan B, Brown Markus A, Euerle Christopher, St Leger Raymond J

Abstract excerpt

Fungi cause the majority of insect disease. However, to date attempts to model host-fungal interactions with Drosophila have focused on opportunistic human pathogens. Here, we performed a screen of 2,613 mutant Drosophila lines to identify host genes affecting susceptibility to the natural insect pathogen Metarhizium anisopliae (Ma549). Overall, 241 (9.22%) mutant lines had altered resistance to Ma549. Life spans...

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Identifiers

PMID: 26202798
DOI: 10.1038/srep12350
PMCID: PMC4511952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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