Article
A collagenous protective coat enables Metarhizium anisopliae to evade insect immune responses.
Proceedings of the National Academy of Sciences of the United States of America - 25 Apr 2006
Wang Chengshu, St Leger Raymond J
Abstract excerpt
The ubiquitous fungal pathogen Metarhizium anisopliae kills a wide range of insects. Host hemocytes can recognize and ingest its conidia, but this capacity is lost on production of hyphal bodies. We show that the unusual ability of hyphal bodies to avoid detection depends on a gene (Mcl1) that is expressed within 20 min of the pathogen contacting hemolymph. A mutant disrupted in Mcl1 is rapidly attacked by...
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