Micro RNA dysregulation in rhabdomyosarcoma: a new player enters the game

Abstract excerpt

Rhabdomyosarcoma (RMS) is the most common of the soft tissue sarcomas with resultant high morbidity, frequently occuring in paediatric patients and young adults. While the molecular basis of RMS has received considerable attention, exact mechanisms underlying its development and metastasis remain unclear. MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that negatively regulate gene expression...

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