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Article

MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality

1 Jan 2011

Abstract excerpt

There is growing evidence that interconnections among molecular pathways governing tissue differentiation are nodal points for malignant transformation. In this scenario, microRNAs appear as crucial players. This class of non-coding small regulatory RNA molecules controls developmental programs by modulating gene expression through post-transcriptional silencing of target mRNAs. During myogenesis, muscle-specific...

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PMID: 21943149
DOI: 10.1186/1476-4598-10-120

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