Article
miRNA-197 and miRNA-184 are associated with brain metastasis in EGFR-mutant lung cancers.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Feb 2016
Remon J, Alvarez-Berdugo D, Majem M, Moran T, Reguart N, Lianes P
Abstract excerpt
INTRODUCTION: The prognostic value of EGFR mutation in lung cancer patients with brain metastases is uncertain and therapeutic efficacy with EGFR TKI is limited. Looking for biomarkers closely related with early tumor changes and brain metastases in non-small cell lung cancer is warranted. MicroRNAs (miRNAs) are frequently deregulated in lung cancer. The objective of this study was to investigate whether some...
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