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Article

Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches.

EMBO molecular medicine - 1 Oct 2015

Di Meo Ivano, Lamperti Costanza, Tiranti Valeria

Abstract excerpt

Mitochondrial disorders are a group of highly invalidating human conditions for which effective treatment is currently unavailable and characterized by faulty energy supply due to defective oxidative phosphorylation (OXPHOS). Given the complexity of mitochondrial genetics and biochemistry, mitochondrial inherited diseases may present with a vast range of symptoms, organ involvement, severity, age of onset, and...

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Source

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Identifiers

PMID: 26194912
DOI: 10.15252/emmm.201505040
PMCID: PMC4604682

Genes

ETHE1
TYMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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