Article
Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish.
Biochemical and biophysical research communications - 2 Oct 2015
Zhang Conghui, Zhang Qi, Wang Fang, Liu Qin
Abstract excerpt
Proteomic analysis of the mouse photoreceptor sensory cilium identified a set of cilia proteins, including Poc1 centriolar protein b (Poc1b). Previous functional studies in human cells and zebrafish embryos implicated that Poc1b plays important roles in centriole duplication and length control, as well as ciliogenesis. To study the function of Poc1b in photoreceptor sensory cilia and other primary cilia, we...
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