Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational Prediction and Validation of BAHD1 as a Novel Molecule for Ulcerative Colitis.

Scientific reports - 17 Jul 2015

Zhu Huatuo, Wan Xingyong, Li Jing, Han Lu, Bo Xiaochen, Chen Wenguo, Lu Chao, Shen Zhe, Xu Chenfu, Chen Lihua, Yu Chaohui, Xu Guoqiang

Abstract excerpt

Ulcerative colitis (UC) is a common inflammatory bowel disease (IBD) producing intestinal inflammation and tissue damage. The precise aetiology of UC remains unknown. In this study, we applied a rank-based expression profile comparative algorithm, gene set enrichment analysis (GSEA), to evaluate the expression profiles of UC patients and small interfering RNA (siRNA)-perturbed cells to predict proteins that might...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockout Techniques

Share to I-kappa B Proteins

Share to Inflammation Mediators

Share to JNK Mitogen-Activated Protein Kinases

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Transcription Factor AP-1

Source

Open in PubMed Open full text

Identifiers

PMID: 26183847
DOI: 10.1038/srep12227
PMCID: PMC4505333

Genes

BAHD1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational Prediction and Validation of BAHD1 as a Novel Molecule for Ulcerative Colitis.PMID 26183847Read ↗

Functional screen of Inflammatory bowel disease genes reveals key epithelial functionsSemantic proximity Read ↗

Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning.Semantic proximity Read ↗

NF-κB pathway related long non-coding RNAs in inflammatory bowel diseaseSemantic proximity Read ↗

Identification of differentially expressed genes in ulcerative colitis and verification in a colitis mouse model by bioinformatics analysesSemantic proximity Read ↗

DEF4A/hBD2, a non-invasive serum biomarker for detection of Ulcerative colitisSemantic proximity Read ↗

Body-wide genetic deficiency of poly(ADP-ribose) polymerase 14 sensitizes mice to colitisSemantic proximity Read ↗

Transcriptome profiling of ulcerative colitis mouse model suggests biomarkers and therapeutic targets for human colitisSemantic proximity Read ↗

Ulcerative Colitis Database: An Integrated Database and Toolkit for Gene Function and Medication Involved in Ulcerative Colitis.Semantic proximity Read ↗

A New Differential Gene Expression Based Simulated Annealing for Solving Gene Selection Problem: A Case Study on Eosinophilic Esophagitis and Few Other Gastro-Intestinal DiseasesSemantic proximity Read ↗

SETD8 involved in the progression of inflammatory bowel disease via epigenetically regulating p62 expressionSemantic proximity Read ↗

DNA methylation fine-tunes pro-and anti-inflammatory signalling pathways in inactive ulcerative colitisSemantic proximity Read ↗

STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.