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Article

Tandem Duplications and the Limits of Natural Selection in Drosophila yakuba and Drosophila simulans.

PloS one - 1 Jan 2015

Rogers Rebekah L, Cridland Julie M, Shao Ling, Hu Tina T, Andolfatto Peter, Thornton Kevin R

Abstract excerpt

Tandem duplications are an essential source of genetic novelty, and their variation in natural populations is expected to influence adaptive walks. Here, we describe evolutionary impacts of recently-derived, segregating tandem duplications in Drosophila yakuba and Drosophila simulans. We observe an excess of duplicated genes involved in defense against pathogens, insecticide resistance, chorion development,...

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PMID: 26176952
DOI: 10.1371/journal.pone.0132184
PMCID: PMC4503668

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