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Article

The challenges associated with molecular targeted therapies for glioblastoma.

Journal of neuro-oncology - 1 May 2016

Jue Toni Rose, McDonald Kerrie L

Abstract excerpt

Glioblastoma (GBM) is the most aggressive malignant brain tumor in adults. Improvements in the treatment of GBM have remained static since the advent of the standard therapy which includes radiation with concurrent and adjuvant temozolomide treatment. Developing treatment and diagnostic or companion biomarker combinations is transforming the way we treat numerous cancers. However, can this emerging paradigm be...

Topics

Antineoplastic Agents
Brain Neoplasms
Glioblastoma
Humans
Molecular Targeted Therapy
Mutation
Neoplasm Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26900075
DOI: 10.1007/s11060-016-2080-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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