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Article

Association of genetic polymorphisms in PRKDC and XRCC4 with risk of ESCC in a high-incidence region of North China.

Tumori - 1 Jan 2000

Yang Hong-Li, Qiao Dong-Dong, Li Kun, Cheng Xiao-Li, Yang Jing, Zhao Jian-Jian, Xu Chang-Qing, Li Yan-Qing

Abstract excerpt

BACKGROUND: The nonhomologous end-joining (NHEJ) pathway is the main mechanism repairing DNA double-strand breaks (DSBs) in human cells. This research was designed to study the association between selected variants in NHEJ members and esophageal squamous cell carcinoma (ESCC). METHODS: Two single...

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Share to Carcinoma, Squamous Cell
Share to DNA-Activated Protein Kinase
Share to DNA End-Joining Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

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Share to Nuclear Proteins

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 26166223
DOI: 10.5301/tj.5000306

Genes

PRKDC
XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26166223-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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