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Article

Identifying Children With Poor Cochlear Implantation Outcomes Using Massively Parallel Sequencing.

Medicine - 1 Jul 2015

Wu Chen-Chi, Lin Yin-Hung, Liu Tien-Chen, Lin Kai-Nan, Yang Wei-Shiung, Hsu Chuan-Jen, Chen Pei-Lung, Wu Che-Ming

Abstract excerpt

Cochlear implantation is currently the treatment of choice for children with severe to profound hearing impairment. However, the outcomes with cochlear implants (CIs) vary significantly among recipients. The purpose of the present study is to identify the genetic determinants of poor CI outcomes. Twelve children with poor CI outcomes (the "cases") and 30 "matched controls" with good CI outcomes were subjected to...

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Source

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Identifiers

PMID: 26166082
DOI: 10.1097/MD.0000000000001073
PMCID: PMC4504554

Genes

PCDH15
ESRRB
GJB3
LRTOMT
WFS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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