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Article

Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing.

Bioscience reports - 25 Jun 2021

Jiang Yi, Wu Lihua, Huang Shasha, Li Pidong, Gao Bo, Yuan Yongyi, Zhang Siwen, Yu Guoliang, Gao Yong, Wu Hao, Dai Pu

Abstract excerpt

X-linked deafness-2 (DFNX2) is cochlear incomplete partition type III (IP-III), one of inner ear malformations characterized by an abnormally wide opening in the bone separating the basal turn of the cochlea from the internal auditory canal, fixation of the stapes and cerebrospinal fluid (CSF) gusher upon stapedectomy or cochleostomy. The causative gene of DFNX2 was POU3F4. To investigate the genetic causes of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33860785
DOI: 10.1042/BSR20203740
PMCID: PMC8193640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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