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Article

Rethinking tamoxifen in the management of melanoma: New answers for an old question.

European journal of pharmacology - 5 Oct 2015

Ribeiro Mariana P C, Santos Armanda E, Custódio José B A

Abstract excerpt

The use of the antiestrogen tamoxifen in melanoma therapy is controversial due to the unsuccessful outcomes and a still rather unclarified mechanism of action. It seemed that the days of tamoxifen in malignant melanoma therapy were close to an end, but new evidence may challenge this fate. On one hand, it is now believed that metabolism is a major determinant of tamoxifen clinical outcomes in breast cancer...

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Share to Antineoplastic Agents, Hormonal
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Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26165763
DOI: 10.1016/j.ejphar.2015.07.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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