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Article

Analysis of Small Fragment Deletions of the APC gene in Chinese Patients with Familial Adenomatous Polyposis, a Precancerous Condition.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Chen Qing-Wei, Zhang Xiao-Mei, Zhou Jian-Nong, Zhou Xin, Ma Guo-Jian, Zhu Ming, Zhang Yuan-Ying, Yu Jun, Feng Ji-Feng, Chen Sen-Qing

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease mainly caused by mutations of the adenomatous polyposis coli (APC) gene with almost complete penetrance. These colorectal polyps are precancerous lesions that will inevitable develop into colorectal cancer at the median age of 40-year old if total proctocolectomy is not performed. So identification of APC germline...

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Source

Identifiers

PMID: 26163615
DOI: 10.7314/apjcp.2015.16.12.4915

Genes

APC
FAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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