Article
DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2016
Hranilovic Dubravka, Blazevic Sofia, Stefulj Jasminka, Zill Peter
Abstract excerpt
Disturbed brain and peripheral serotonin homeostasis is often found in subjects with autism spectrum disorder (ASD). The role of the serotonin receptor 2A (HTR2A) in the regulation of central and peripheral serotonin homeostasis, as well as its altered expression in autistic subjects, have implicated the HTR2A gene as a major candidate for the serotonin disturbance seen in autism. Several studies, yielding so far...
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