Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP 53 polymorphisms and melanoma: A meta-analysis.

Journal of cancer research and therapeutics - 1 Jan 2000

He Ting, Wu Jinhu, Chen Yong, Zhang Junzhi

Abstract excerpt

BACKGROUND: p53 is a tumor suppressor encoded by the TP53 gene. It is critical in activating deoxyribonucleic acid (DNA) repair upon damage, and thus preserving genomic stability. TP53 is implicated in tumor progression. Melanoma results from transformed melanocytes in the skin. Data gathered on the association between the TP53 Arg72, Pro72 (rs1042522; G>C) polymorphism and melanoma are conflicting. AIMS: To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Melanoma

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 26148609
DOI: 10.4103/0973-1482.157329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP 53 polymorphisms and melanoma: A meta-analysis.PMID 26148609Read ↗

Arg72Pro polymorphism of TP53 gene and the risk of skin cancer: a meta-analysis.Semantic proximity Read ↗

TP53 Arg72Pro polymorphism and skin cancer risk: a meta-analysis.Semantic proximity Read ↗

Increased risk of cutaneous melanoma associated with p53 Arg72Pro polymorphism.Semantic proximity Read ↗

p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma.Semantic proximity Read ↗

The role of TP53 and MDM2 polymorphisms in TP53 mutagenesis and risk of non-melanoma skin cancer.Semantic proximity Read ↗

p53 codon 72 Pro homozygosity increases the risk of cutaneous melanoma in individuals with dark skin complexion and among noncarriers of melanocortin 1 receptor red hair variants.Semantic proximity Read ↗

p53 codon 72 polymorphisms and random amplified polymorphic DNA analysis of non-melanoma skin cancer through archival formalin-fixed paraffin-embedded tissue.Semantic proximity Read ↗

TP53 codon 72 polymorphism in pigmentary phenotypes.Semantic proximity Read ↗

p.Arg72Pro polymorphism of P53 and breast cancer risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

No Evidence of Association of the Arg72Pro p53 Gene Polymorphism with Cancer Risk in the Saudi Population: a Meta-Analysis.Semantic proximity Read ↗

Mutations and polymorphisms in TP53 gene--an overview on the role in colorectal cancer.Semantic proximity Read ↗

Arg72Pro TP53 polymorphism and cancer susceptibility: a comprehensive meta-analysis of 302 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.