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Article

Frequent FOS Gene Rearrangements in Epithelioid Hemangioma: A Molecular Study of 58 Cases With Morphologic Reappraisal.

The American journal of surgical pathology - 1 Oct 2015

Huang Shih-Chiang, Zhang Lei, Sung Yun-Shao, Chen Chun-Liang, Krausz Thomas, Dickson Brendan C, Kao Yu-Chien, Agaram Narasimhan P, Fletcher Christopher D M, Antonescu Cristina R

Abstract excerpt

Epithelioid hemangioma (EH) is a unique benign vasoformative tumor composed of epithelioid endothelial cells. Although a small subset of EHs with atypical features harbor ZFP36-FOSB fusions, no additional genetic abnormalities have been found to date in the remaining cases. On the basis of a novel FOS-LMNA gene fusion identified by RNA sequencing in an index case of a skeletal EH with typical morphology, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, fos

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Share to In Situ Hybridization, Fluorescence

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Source

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Identifiers

PMID: 26135557
DOI: 10.1097/PAS.0000000000000469
PMCID: PMC4567921

Genes

FOS
FOSB
LMNA
ZFP36

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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