Article
Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics.
Scientific reports - 2 Jul 2015
Goto Noriko, Bazar Gyorgy, Kovacs Zoltan, Kunisada Makoto, Morita Hiroyuki, Kizaki Seiichiro, Sugiyama Hiroshi, Tsenkova Roumiana, Nishigori Chikako
Abstract excerpt
Ultraviolet (UV) radiation causes cellular DNA damage, among which cyclobutane pyrimidine dimers (CPDs) are responsible for a variety of genetic mutations. Although several approaches have been developed for detection of CPDs, conventional methods require time-consuming steps. Aquaphotomics, a new approach based on near-infrared spectroscopy (NIRS) and multivariate analysis that determines interactions between...
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