Article
Association between an alternative promoter polymorphism and sperm deformity rate is due to modulation of the expression of KATNAL1 transcripts in Chinese Holstein bulls.
Animal genetics - 1 Oct 2014
Zhang X, Wang C, Zhang Y, Ju Z, Qi C, Wang X, Huang J, Zhang S, Li J, Zhong J, Shi F
Abstract excerpt
Katanin p60 subunit A-like 1 (KATNAL1) is an ATPase that regulates Sertoli cell microtubule dynamics and sperm retention. We evaluated one novel splice variant and characterized the promoter and a functional single nucleotide polymorphism (SNP) of the bovine KATNAL1 gene to explore its expression pattern, possible regulatory mechanism and relationship with semen traits in Chinese Holstein bulls. A novel splice...
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