Article
Co-selection and replacement of resistance alleles to Lysinibacillus sphaericus in a Culex quinquefasciatus colony.
The FEBS journal - 1 Sept 2015
Chalegre Karlos Diogo de Melo, Tavares Daniella A, Romão Tatiany P, de Menezes Heverly Suzany G, Nascimento Nathaly A, de Oliveira Cláudia Maria F, de-Melo-Neto Osvaldo P, Silva-Filha Maria Helena N L
Abstract excerpt
The Cqm1 α-glucosidase, expressed within the midgut of Culex quinquefasciatus mosquito larvae, is the receptor for the Binary toxin (Bin) from the entomopathogen Lysinibacillus sphaericus. Mutations of the Cqm1 α-glucosidase gene cause high resistance levels to this bacterium in both field and laboratory populations, and a previously described allele, cqm1REC, was found to be associated with a...
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