Article
Detection of an allele conferring resistance to Bacillus sphaericus binary toxin in Culex quinquefasciatus populations by molecular screening.
Applied and environmental microbiology - 1 Feb 2009
Chalegre Karlos Diogo de Melo, Romão Tatiany Patrícia, Amorim Liliane Barbosa, Anastacio Daniela Bandeira, de Barros Rosineide Arruda, de Oliveira Cláudia Maria Fontes, Regis Lêda, de-Melo-Neto Osvaldo Pompílio, Silva-Filha Maria Helena Neves Lobo
Abstract excerpt
The activity of the Bacillus sphaericus binary (Bin) toxin on Culex quinquefasciatus larvae depends on its specific binding to the Cqm1 receptor, a midgut membrane-bound alpha-glucosidase. A 19-nucleotide deletion in the cqm1 gene (cqm1(REC)) mediates high-level resistance to Bin toxin. Here, resistance in nontreated and B. sphaericus-treated field populations of C. quinquefasciatus was assessed through bioassays...
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