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Article

Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model.

BMC medical genomics - 30 Jun 2015

Grilli A, Sciandra M, Terracciano M, Picci P, Scotlandi K

Abstract excerpt

BACKGROUND: microRNAs (miRs) are small non-coding RNAs involved in the fine regulation of several cellular processes by inhibiting their target genes at post-transcriptional level. Osteosarcoma (OS) is a tumor thought to be related to a molecular blockade of the normal process of osteoblast differentiation. The current paper explores temporal transcriptional modifications comparing an osteosarcoma cell line,...

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Identifiers

PMID: 26123714
DOI: 10.1186/s12920-015-0106-0
PMCID: PMC4486310

Genes

AKT1
MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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