Article
Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model.
BMC medical genomics - 30 Jun 2015
Grilli A, Sciandra M, Terracciano M, Picci P, Scotlandi K
Abstract excerpt
BACKGROUND: microRNAs (miRs) are small non-coding RNAs involved in the fine regulation of several cellular processes by inhibiting their target genes at post-transcriptional level. Osteosarcoma (OS) is a tumor thought to be related to a molecular blockade of the normal process of osteoblast diffe...
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