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Article

Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates.

BMC evolutionary biology - 30 Jun 2015

Shi Lei, Lin Qiang, Su Bing

Abstract excerpt

BACKGROUND: Sexual dimorphism in brain size is common among primates, including humans, apes and some Old World monkeys. In these species, the brain size of males is generally larger than that of females. Curiously, this dimorphism has persisted over the course of primate evolution and human origin, but there is no explanation for the underlying genetic controls that have maintained this disparity in brain size....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26123139
DOI: 10.1186/s12862-015-0398-x
PMCID: PMC4487212

Genes

ASPM
MCPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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