Article
Ohr Protects Corynebacterium glutamicum against Organic Hydroperoxide Induced Oxidative Stress.
PloS one - 1 Jan 2015
Si Meiru, Wang Jianbo, Xiao Xiao, Guan Jingyuan, Zhang Yaoling, Ding Wei, Chaudhry Muhammad Tausif, Wang Yao, Shen Xihui
Abstract excerpt
Ohr, a bacterial protein encoded by the Organic Hydroperoxide Resistance (ohr) gene, plays a critical role in resistance to organic hydroperoxides. In the present study, we show that the Cys-based thiol-dependent Ohr of Corynebacterium glutamicum decomposes organic hydroperoxides more efficiently than hydrogen peroxide. Replacement of either of the two Cys residues of Ohr by a Ser residue resulted in drastic loss...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
