Genetic Polymorphisms Associated with Hearing Threshold Shift in Subjects during First Encounter with Occupational Impulse Noise.

doi:10.1371/journal.pone.0130827

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Article

Genetic Polymorphisms Associated with Hearing Threshold Shift in Subjects during First Encounter with Occupational Impulse Noise.

PloS one - 1 Jan 2015

Grondin Yohann, Bortoni Magda E, Sepulveda Rosalinda, Ghelfi Elisa, Bartos Adam, Cotanche Douglas, Clifford Royce E, Rogers Rick A

Abstract excerpt

Noise-induced hearing loss (NIHL) is the most significant occupational health issue worldwide. We conducted a genome-wide association study to identify single-nucleotide polymorphisms (SNPs) associated with hearing threshold shift in young males undergoing their first encounter with occupational impulse noise. We report a significant association of SNP rs7598759 (p < 5 x 10(-7); p = 0.01 after permutation and...

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PMID: 26121033
DOI: 10.1371/journal.pone.0130827
PMCID: PMC4488244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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