Article
Association of TagSNP in lncRNA HOTAIR with susceptibility to noise-induced hearing loss in a Chinese population.
Hearing research - 1 Apr 2017
Wang Boshen, Ding Enmin, Shen Huanxi, Wang Jianfeng, Sun Kai, Chen Shi, Han Lei, Zhang Hengdong, Zhu Baoli, Xu Ming
Abstract excerpt
BACKGROUND: Noise-induced hearing loss (NIHL) is a multifactorial disease, and dysregulation of oxidative stress is universally acknowledged as one crucial pathogenic factor for this disease. Recently studies have found the LncRNA HOTAIR is involved in the alteration of oxidative stress level, cell proliferation, cell cycle progression, and apoptosis. Considering the effects of lncRNA HOTAIR in cellular oxidative...
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