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Article

Polymorphisms of the IL27 gene in a Chinese Han population complicated with pre-eclampsia.

Scientific reports - 14 Mar 2016

Liu Bin, Li Yuan, Yao Yuan, Li Hua, Liang Hongda, Xin Miaomiao, Wang Liqin, Zhao Lei, Lin Jizheng, Liu Shiguo

Abstract excerpt

IL-27 could inhibit the development of Th17 cells, and the Th17/regulatory T-cell imbalance may reverse maternal tolerance in pre-eclampsia (PE). The aim of this study was to investigate the association between genetic polymorphisms in IL27 with PE. Three SNPs in IL27 (rs153109, rs17855750, and rs181206) were genotyped in a Chinese Han cohort of 1040 PE patients and 1247 normal pregnant women using the TaqMan...

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Identifiers

PMID: 26971578
DOI: 10.1038/srep23029
PMCID: PMC4789744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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