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Article

SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value.

Blood - 12 Jan 2012

Patnaik Mrinal M, Lasho Terra L, Hodnefield Janice M, Knudson Ryan A, Ketterling Rhett P, Garcia-Manero Guillermo, Steensma David P, Pardanani Animesh, Hanson Curtis A, Tefferi Ayalew

Abstract excerpt

SF3B1 mutations were recently reported in myelodysplastic syndromes (MDSs), especially in the presence of ring sideroblasts (RSs). We sought to define the interaction between SF3B1 mutations, morphology, karyotype, and prognosis in MDS with more than or equal to 15% RS (MDS-RS). We studied 107 patients with MDS-RS, including 48 with refractory anemia with RS (RARS), 43 with refractory cytopenia with multilineage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22096241
DOI: 10.1182/blood-2011-09-377994
PMCID: PMC4916563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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