Article
Wolbachia Reduces the Transmission Potential of Dengue-Infected Aedes aegypti.
PLoS neglected tropical diseases - 1 Jan 2015
Ye Yixin H, Carrasco Alison M, Frentiu Francesca D, Chenoweth Stephen F, Beebe Nigel W, van den Hurk Andrew F, Simmons Cameron P, O'Neill Scott L, McGraw Elizabeth A
Abstract excerpt
BACKGROUND: Dengue viruses (DENV) are the causative agents of dengue, the world's most prevalent arthropod-borne disease with around 40% of the world's population at risk of infection annually. Wolbachia pipientis, an obligate intracellular bacterium, is being developed as a biocontrol strategy against dengue because it limits replication of the virus in the mosquito. The Wolbachia strain wMel, which has been...
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