Article
Novel phenotype of Wolbachia strain wPip in Aedes aegypti challenges assumptions on mechanisms of Wolbachia-mediated dengue virus inhibition.
PLoS pathogens - 1 Jul 2020
Fraser Johanna E, O'Donnell Tanya B, Duyvestyn Johanna M, O'Neill Scott L, Simmons Cameron P, Flores Heather A
Abstract excerpt
The bacterial endosymbiont Wolbachia is a biocontrol tool that inhibits the ability of the Aedes aegypti mosquito to transmit positive-sense RNA viruses such as dengue and Zika. Growing evidence indicates that when Wolbachia strains wMel or wAlbB are introduced into local mosquito populations, human dengue incidence is reduced. Despite the success of this novel intervention, we still do not fully understand how...
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