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The Effect of Temperature on Wolbachia-Mediated Dengue Virus Blocking in Aedes aegypti

9 Feb 2016

Abstract excerpt

Dengue fever, caused by dengue virus (DENV), is endemic in more than 100 countries. The lack of effective treatment of patients and the suboptimal efficacies of the tetravalent vaccine in trials highlight the urgent need to develop alternative strategies to lessen the burden of dengue fever.Wolbachia pipientis, an obligate intracellular bacterium, is being developed as a biocontrol strategy against dengue because...

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PMID: 26856916
DOI: 10.4269/ajtmh.15-0801

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