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Article

Isocitrate dehydrogenase 1 Gene Mutation Is Associated with Prognosis in Clinical Low-Grade Gliomas.

PloS one - 1 Jan 2015

Li Ming-Yang, Wang Yin-Yan, Cai Jin-Quan, Zhang Chuan-Bao, Wang Kuan-Yu, Cheng Wen, Liu Yan-Wei, Zhang Wei, Jiang Tao

Abstract excerpt

Isocitrate dehydrogenase 1 gene mutations are found in most World Health Organization grade II and III gliomas and secondary glioblastomas. Isocitrate dehydrogenase 1 mutations are known to have prognostic value in high-grade gliomas. However, their prognostic significance in low-grade gliomas remains controversial. We determined the predictive and prognostic value of isocitrate dehydrogenase 1 status in...

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Identifiers

PMID: 26115094
DOI: 10.1371/journal.pone.0130872
PMCID: PMC4482584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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